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Primeur weekly 2014-11-10

Special

Explicit Vector Programming with OpenMP 4.0 SIMD Extensions ...

Focus

BIG project develops roadmaps to respond to Big Data opportunities in Europe ...

Embassy Cloud is bringing bio-informatic data analysis to computing and data services infrastructure ...

ANSYS to introduce engineering simulation applications in the Cloud ...

The Cloud

ConPaaS team to release ConPaaS 1.4.2 ...

IBM unveils industry's first intelligent Cloud security portfolio for global businesses ...

EuroFlash

ISC 2015 programme to offer greater diversity ...

Saving lots of computing capacity with a new algorithm ...

New research lights the way to super-fast computers ...

University of Edinburgy - EPCC to issue Call for Participation for the Exascale Applications and Software Conference ...

Two photons strongly coupled by glass fiber ...

HP and Wind River partner to create carrier grade HP Helion OpenStack solutions for NFV ...

Bull to issue Q3 financial results ...

USFlash

Chematria launches search for new Ebola treatments using artificial intelligence ...

HP delivers Flash Storage performance and efficiency without complexity of rip-and-replace ...

Industry collaboration drives 100G foundation for supercomputer infrastructure ...

TACC to expand with $20 million new building in 2016 ...

NVIDIA announces financial results for third quarter fiscal 2015 ...

Stream Integration Announces Availability of the Stream Grid Workbench ...

Oracle announces latest release of Oracle Database Appliance software ...

Eurocom's mobile supercomputer now supports the most powerful graphics, NVIDIA GTX 980M in SLI ...

Chematria launches search for new Ebola treatments using artificial intelligence

4 Nov 2014 Toronto - Chematria Inc. and the University of Toronto have launched an initiative to search for new treatments for the Ebola virus using artificial intelligence. Deploying a groundbreaking research technology that learns and thinks like a human chemist, the team will use Canada's most powerful supercomputer to simulate and analyze millions of potential medicines in a matter of weeks. Like software used to design airplanes and computer chips in simulation, this new system can predict the possible effectiveness of new medicines, without the need for costly and time-consuming physical synthesis and testing.

The World Health Organization has projected that new cases of Ebola could reach 10,000 each week by December, underscoring the urgent need for research to address the crisis. The unprecedented speed and scale of this investigation is enabled by the unique strengths of three partners: Chematria Inc. is offering the core artificial intelligence technology that performs the drug research. The University of Toronto is contributing biological insights about Ebola that the system will exploit to search for new treatments. IBM Inc. is supplying the supercomputer, a 64,000-CPU Blue Gene/Q.

"What we are attempting would have been considered science fiction, until now", stated Chematria CEO, Dr. Abraham Heifets. "We are going to explore the possible effectiveness of millions of drugs, something that used to take decades of physical research and tens of millions of dollars, in mere days with our technology."

Chematria's technology is a virtual drug discovery platform based on the science of Deep Learning Neural Networks, and has previously been used for research on Malaria, Multiple Sclerosis, C. Difficile, and Leukemia. The system is driven by a virtual brain, modeled on the human visual cortex, that teaches itself by "studying" millions of datapoints about how drugs have worked in the past. With this vast knowledge, Chematria's brain can apply the patterns it perceives to predict the effectiveness of hypothetical drugs, and suggest surprising uses for existing drugs, transforming the way medicines are discovered.

The Ebola initiative will exploit critical biological insights about how the virus replicates. "Our team is focusing on the mechanism Ebola uses to latch on to the cells it infects", stated Dr. Jeffrey Lee of the University of Toronto. "Interrupting that process with a new drug could prevent the virus from replicating, and potentially work against other viruses like Marburg and HIV that use the same mechanism." While there are "broad spectrum" antibiotics that can treat multiple kinds of bacterial infections, most antiviral medications are only effective against a single kind of virus.

The initiative may also demonstrate an alternative approach to high-speed medical research. While giving drugs to patients will always require thorough clinical testing, zeroing in on the best drug candidates can take years using today's most common methods. This slow and prohibitively expensive process is one of the key reasons that finding treatments for rare and emerging diseases is difficult.

"If we can find promising drug candidates for Ebola using computers alone", stated Abraham Heifets. "It will be a milestone for how we develop cures."
Source: Chematria

Back to Table of contents

Primeur weekly 2014-11-10

Special

Explicit Vector Programming with OpenMP 4.0 SIMD Extensions ...

Focus

BIG project develops roadmaps to respond to Big Data opportunities in Europe ...

Embassy Cloud is bringing bio-informatic data analysis to computing and data services infrastructure ...

ANSYS to introduce engineering simulation applications in the Cloud ...

The Cloud

ConPaaS team to release ConPaaS 1.4.2 ...

IBM unveils industry's first intelligent Cloud security portfolio for global businesses ...

EuroFlash

ISC 2015 programme to offer greater diversity ...

Saving lots of computing capacity with a new algorithm ...

New research lights the way to super-fast computers ...

University of Edinburgy - EPCC to issue Call for Participation for the Exascale Applications and Software Conference ...

Two photons strongly coupled by glass fiber ...

HP and Wind River partner to create carrier grade HP Helion OpenStack solutions for NFV ...

Bull to issue Q3 financial results ...

USFlash

Chematria launches search for new Ebola treatments using artificial intelligence ...

HP delivers Flash Storage performance and efficiency without complexity of rip-and-replace ...

Industry collaboration drives 100G foundation for supercomputer infrastructure ...

TACC to expand with $20 million new building in 2016 ...

NVIDIA announces financial results for third quarter fiscal 2015 ...

Stream Integration Announces Availability of the Stream Grid Workbench ...

Oracle announces latest release of Oracle Database Appliance software ...

Eurocom's mobile supercomputer now supports the most powerful graphics, NVIDIA GTX 980M in SLI ...