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Primeur weekly 2012-10-08

The Cloud

ISC Cloud’12 shared new evolution images from HPC and big data in the Cloud ...

Bright Computing to present data aware Cloud bursting to the SLURM User Group ...

Oracle unveils expanded Oracle Cloud Services portfolio ...

Oracle extends Oracle Communications Billing and Revenue Management product family with innovative Oracle Communications Elastic Charging Engine ...

Oracle Enterprise Manager 12c introduces new tools and programmes for partners ...

Fujitsu Cloud solution bolsters Ritsumeikan Asia Pacific University's administrative information system ...

Lending Club selects Oracle ERP Cloud Service to help increase insight and efficiencies ...

Customers live on Oracle Fusion Human Capital Management ...

Oracle continues to extend industry's no. 1 business innovation platform for the enterprise and the Cloud ...

Kwality Dairy selects IBM Cloud to drive supply chain efficiencies ...

Oracle announces ISV integration with Oracle Sales and Marketing Cloud Service ...

Oracle unveils new partner Cloud programmes at Oracle OpenWorld 2012 ...

Fujitsu Cloud solution enhances Kansai University's educational research system platform ...

HP advances software-defined networks with integrated infrastructure, controller and application solutions ...

Oracle announces Oracle Solaris 11.1 at Oracle OpenWorld ...

VMware simplifies compliance for business-critical applications in the Cloud ...

Desktop Grids

OProject@Home has been launched ...

EuroFlash

Altair's latest Compute Manager offers built-in 3D and 2D visualization of high-performance computing simulations ...

Green Brain project to create an autonomous flying robot with a honey bee brain ...

Hi-fi single photons ...

USFlash

Indiana University develops tool to improve NASA polar ice mission ...

Launch of the USA's fastest Genomic Supercomputing Platform reduces cancer genome analysis from months to seconds - One patient every 47 seconds ...

South Australian Research Facility unleashes the Tizard supercomputer ...

Mellanox InfiniBand selected by Fujitsu to accelerate the Australian National University supercomputer ...

Oracle announces Oracle Exadata X3 Database In-Memory Machine ...

Virginia Tech to tackle the Big Data challenges of next-generation sequencing with HokieSpeed ...

Iowa State researchers developing Big Data toolbox to help genome researchers ...

IBM completes acquisition of Texas Memory Systems ...

Brown University awarded $1.5 million for new Big Data tools ...

Cognitech Inc. announces release of industry's fastest mobile and tower supercomputing Forensic Video Workstations ...

Dell Smart Grid Data Management Solution enables utility companies to improve efficiency ...

New Zealand Freight Service provider adopts IBM PureSystems for IT consolidation ...

IBM boosts security, Cloud and analytics capabilities with new Power systems, storage and mainframe technologies ...

Sandia builds Android-based network to study cyber disruptions ...

Sandia gains national recognition for sustainable energy management ...

NSF announces interagency progress on administration's Big Data initiative ...

National Science Foundation awards Rutgers $1.4 million to help create ways to analyze Big Data ...

Brown University awarded $1.5 million for new Big Data tools

3 Oct 2012 Providence - Computer scientists from Brown University have been awarded $1.5 million to develop new computer algorithms and statistical methods to analyze large, complex datasets. Funding for the project comes from a joint initiative of the National Science Foundation and the National Institutes of Health aimed at supporting fundamental research on Big Data.

Eli Upfal, professor of computer science, will lead the research with fellow computer science professors Ben Raphael and Fabio Vandin. Brown's funding allotment is the second largest of the eight grants awarded under the programme this year, according to the official NSF/NIH announcement.

Eli Upfal and his colleagues will test their new methods on genomics data. Nowhere are the challenges of Big Data more evident than in genomics. As techniques for sequencing genes have become faster and cheaper, researchers have compiled mountains of new data. The trick now is trying to make sense of it all - picking out significant trends and ignoring all the unimportant "noise" that inevitably accumulates in large datasets.

"These datasets have all the good and bad properties of Big Data", Eli Upfal stated. "They're big, noisy, and require very complicated statistical analysis to obtain useful information."

One of the aims of this project is to develop better computational tools to isolate genetic mutations that drive cancer by comparing gene sequences of healthy tissue to those of cancerous tissue. The problem is that not every mutation found in cancerous cells is important. There could be thousands of mutations in each cell that don't actually contribute to cancer growth. They're simply insignificant, random mutations. An effective computer algorithm will be able to identify with statistical certainty the mutations that actually matter, keeping doctors from chasing millions of red herrings.

But that's not the only problem Upfal and his team will try to address. There's also the fact that the lab tools used to sequence genes sometimes record information inaccurately. The error rate varies between sequencing techniques but it's significant, and analytical tools need to deal with that problem as well.

One of the thrusts of the Brown project is finding algorithms that address these problems in a way that can be verified statistically. The output of traditional machine learning algorithms, Eli Upfal said, is generally not confirmed in an objective way. Take search engines as an example. If the search algorithm consistently returns the kinds of results users are looking for, they'll keep using it and the algorithm will be deemed successful. But that evaluation is subjective and largely unquantifiable.

"In scientific applications, you need something that can be analyzed rigorously", Eli Upfal stated. "We need to know the confidence level of the outcome." So a key aspect of this project will be combining traditional machine learning algorithms with the most rigorous of statistical methods.

Daunting as the obstacles may be, Upfal and his colleagues have already had success in addressing them. Last year they developed an algorithm called HotNet that helps to isolate clusters of mutated genes that can cause cancer. They're hoping to build on that success with this new grant.

Ultimately, Eli Upfal said, the team hopes to develop new tools that can be broadly applied not only to genomics data but also to other Big Data problems like the analysis of large-scale social networks.
Source: Brown University

Back to Table of contents

Primeur weekly 2012-10-08

The Cloud

ISC Cloud’12 shared new evolution images from HPC and big data in the Cloud ...

Bright Computing to present data aware Cloud bursting to the SLURM User Group ...

Oracle unveils expanded Oracle Cloud Services portfolio ...

Oracle extends Oracle Communications Billing and Revenue Management product family with innovative Oracle Communications Elastic Charging Engine ...

Oracle Enterprise Manager 12c introduces new tools and programmes for partners ...

Fujitsu Cloud solution bolsters Ritsumeikan Asia Pacific University's administrative information system ...

Lending Club selects Oracle ERP Cloud Service to help increase insight and efficiencies ...

Customers live on Oracle Fusion Human Capital Management ...

Oracle continues to extend industry's no. 1 business innovation platform for the enterprise and the Cloud ...

Kwality Dairy selects IBM Cloud to drive supply chain efficiencies ...

Oracle announces ISV integration with Oracle Sales and Marketing Cloud Service ...

Oracle unveils new partner Cloud programmes at Oracle OpenWorld 2012 ...

Fujitsu Cloud solution enhances Kansai University's educational research system platform ...

HP advances software-defined networks with integrated infrastructure, controller and application solutions ...

Oracle announces Oracle Solaris 11.1 at Oracle OpenWorld ...

VMware simplifies compliance for business-critical applications in the Cloud ...

Desktop Grids

OProject@Home has been launched ...

EuroFlash

Altair's latest Compute Manager offers built-in 3D and 2D visualization of high-performance computing simulations ...

Green Brain project to create an autonomous flying robot with a honey bee brain ...

Hi-fi single photons ...

USFlash

Indiana University develops tool to improve NASA polar ice mission ...

Launch of the USA's fastest Genomic Supercomputing Platform reduces cancer genome analysis from months to seconds - One patient every 47 seconds ...

South Australian Research Facility unleashes the Tizard supercomputer ...

Mellanox InfiniBand selected by Fujitsu to accelerate the Australian National University supercomputer ...

Oracle announces Oracle Exadata X3 Database In-Memory Machine ...

Virginia Tech to tackle the Big Data challenges of next-generation sequencing with HokieSpeed ...

Iowa State researchers developing Big Data toolbox to help genome researchers ...

IBM completes acquisition of Texas Memory Systems ...

Brown University awarded $1.5 million for new Big Data tools ...

Cognitech Inc. announces release of industry's fastest mobile and tower supercomputing Forensic Video Workstations ...

Dell Smart Grid Data Management Solution enables utility companies to improve efficiency ...

New Zealand Freight Service provider adopts IBM PureSystems for IT consolidation ...

IBM boosts security, Cloud and analytics capabilities with new Power systems, storage and mainframe technologies ...

Sandia builds Android-based network to study cyber disruptions ...

Sandia gains national recognition for sustainable energy management ...

NSF announces interagency progress on administration's Big Data initiative ...

National Science Foundation awards Rutgers $1.4 million to help create ways to analyze Big Data ...