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Primeur weekly 2012-10-08

The Cloud

ISC Cloud’12 shared new evolution images from HPC and big data in the Cloud ...

Bright Computing to present data aware Cloud bursting to the SLURM User Group ...

Oracle unveils expanded Oracle Cloud Services portfolio ...

Oracle extends Oracle Communications Billing and Revenue Management product family with innovative Oracle Communications Elastic Charging Engine ...

Oracle Enterprise Manager 12c introduces new tools and programmes for partners ...

Fujitsu Cloud solution bolsters Ritsumeikan Asia Pacific University's administrative information system ...

Lending Club selects Oracle ERP Cloud Service to help increase insight and efficiencies ...

Customers live on Oracle Fusion Human Capital Management ...

Oracle continues to extend industry's no. 1 business innovation platform for the enterprise and the Cloud ...

Kwality Dairy selects IBM Cloud to drive supply chain efficiencies ...

Oracle announces ISV integration with Oracle Sales and Marketing Cloud Service ...

Oracle unveils new partner Cloud programmes at Oracle OpenWorld 2012 ...

Fujitsu Cloud solution enhances Kansai University's educational research system platform ...

HP advances software-defined networks with integrated infrastructure, controller and application solutions ...

Oracle announces Oracle Solaris 11.1 at Oracle OpenWorld ...

VMware simplifies compliance for business-critical applications in the Cloud ...

Desktop Grids

OProject@Home has been launched ...

EuroFlash

Altair's latest Compute Manager offers built-in 3D and 2D visualization of high-performance computing simulations ...

Green Brain project to create an autonomous flying robot with a honey bee brain ...

Hi-fi single photons ...

USFlash

Indiana University develops tool to improve NASA polar ice mission ...

Launch of the USA's fastest Genomic Supercomputing Platform reduces cancer genome analysis from months to seconds - One patient every 47 seconds ...

South Australian Research Facility unleashes the Tizard supercomputer ...

Mellanox InfiniBand selected by Fujitsu to accelerate the Australian National University supercomputer ...

Oracle announces Oracle Exadata X3 Database In-Memory Machine ...

Virginia Tech to tackle the Big Data challenges of next-generation sequencing with HokieSpeed ...

Iowa State researchers developing Big Data toolbox to help genome researchers ...

IBM completes acquisition of Texas Memory Systems ...

Brown University awarded $1.5 million for new Big Data tools ...

Cognitech Inc. announces release of industry's fastest mobile and tower supercomputing Forensic Video Workstations ...

Dell Smart Grid Data Management Solution enables utility companies to improve efficiency ...

New Zealand Freight Service provider adopts IBM PureSystems for IT consolidation ...

IBM boosts security, Cloud and analytics capabilities with new Power systems, storage and mainframe technologies ...

Sandia builds Android-based network to study cyber disruptions ...

Sandia gains national recognition for sustainable energy management ...

NSF announces interagency progress on administration's Big Data initiative ...

National Science Foundation awards Rutgers $1.4 million to help create ways to analyze Big Data ...

Launch of the USA's fastest Genomic Supercomputing Platform reduces cancer genome analysis from months to seconds - One patient every 47 seconds

3 Oct 2012 Washington - Dr. Patrick Soon-Shiong, Chairman of NantHealth and the Chan Soon-Shiong Institute for Advanced Health, has achieved a revolutionary advance in cancer treatment that will reduce the necessary time for analysis from 8 weeks to an unprecedented 47 seconds per patient. For the first time, oncologists can compare virtually every known treatment option on the basis of genetics, risk, and cost - before treatment begins, not after.

Alongside Senator Bill Frist, MD, of the Bipartisan Policy Center and J. Michael McGinnis, MD of the Institute of Medicine and Doctors Helping Doctors, Dr. Soon-Shiong reported on the successful real-time analysis of the largest collection of tumor genomes in the United States, of 6,017 cancer genomes from 3,022 patients with 19 different cancer types, in the record time of 69 hours. Genomic analysis has taken an average of 8 to 10 weeks to complete. That delay leads not just to less efficient, more costly care, but sometimes to the wrong course of treatment altogether - and, thus, higher mortality. "Incorrect care that leads to loss of life is unacceptable", stated Dr. Soon-Shiong, "and from today onward, it will no longer be necessary."

Oncologists currently prescribe a course of cancer treatment based on the anatomical location of the cancer. Yet a patient with breast cancer could benefit from the positive results discovered from a patient with lung cancer, if the underlying molecular pathways involving both cancers were the same. The inability to utilize genomic sequencing to guide treatment has been due to the inability to convert a patient's DNA into actionable information in actionable time.

But by collaborating with Blue Shield of California, the Chan Soon-Shiong Institute for Advanced Health, the National LambdaRail, Doctors Helping Doctors, Verizon, Bank of America, AT&T, Intel, and Hewlett-Packard, NantHealth has built a supercomputer-based high-speed fiber network that will not only provide thousands of oncology practices with life-saving information, but do so in exponentially faster time. "Doctors will finally be able to provide higher-quality treatment in a dramatically more efficient, effective, and affordable manner", stated Dr. Soon-Shiong.

"It currently takes approximately two months and tens of thousands of dollars to perform the sequencing and analysis of a single cancer patient’s genome. We can't reduce the cost of care and improve outcomes in cancer if we don't have the capability to know the right treatment for the right patient before treatment begins. We needed a national supercomputing infrastructure that brings genomic medicine into clinical practice. By placing supercomputers in the hands of physicians, that need is now a reality", stated Dr. Soon-Shiong.

Accuracy will also be radically improved. Among NantHealth's partner oncologists utilizing its fact-based software platform, the number of cases where doctors have made incorrect recommendations has dropped from 32% to virtually zero. "With this patient-centred, fact-based approach to collecting and analyzing data, millions more patients will have a better chance of beating cancer", Dr. Soon-Shiong emphasized. Over the past 12 months over 2,000 oncology practices representing 8,000 oncologists and nurses have successfully installed and utilized this fact-based (eviti) software platform, positively impacting thousands of cancer patients lives.

In July 2012, NantWorks' scientific team collected 6,017 tumor and germline exomes, representing 3,022 cancer patients with 19 unique cancer types. The sample collection included: 999 breast cancer; 1,156 kidney and bladder cancer; 985 gastro-intestinal cancer; 744 brain cancer; 745 lung cancer; 670 ovarian, uterine, and cervical cancer; 436 head and neck cancer; 177 prostate cancer; 70 melanoma cancer; and 35 blood tumour samples.

This massive amount of data totaled 96,512 gigabytes and was successfully transferred and processed via a supercomputing, high-speed fiber network in 69 hours. This overall transfer speed represents a stream of one sample every 17.4 seconds, and the supercomputer analysis for genetic and protein alterations between the tumour and normal sample completed every 47 seconds per patient.

Given the nation's estimated cancer rate of 1.8 million new cases in 2012, this infrastructure now brings the capability of analyzing 5,000 patients per day.

Dr. Soon-Shiong noted that medicine has continued to make dramatic advances, but the delivery of medicine has lagged far behind, stuck in a world where information is trapped, patterns get missed, and patients suffer. Powered by advanced supercomputing technology and wireless mobile health, the network has become one of country's fastest genomic platforms with connectivity to over 8000 practising oncologists and nurses. "This revolution in health care is long overdue - converging 21st century medical science with 21st century technology", Dr. Soon-Shiong concluded.

Through NantHealth's genomic analysis network, doctors can finally make cancer treatment more efficient, more effective, and more affordable for more patients. And with public and private partners equally as committed to reshaping the way doctors deliver health care and treat cancer, there are no limits to what this health information breakthrough might lead to for all cancer patients.

A network of major cancer centres including those at City of Hope, John Wayne Cancer Institute, and Methodist Hospital in Houston, have contributed to this collection of over 6,000 genomes, which also included the entire collection of exome samples from The Cancer Genome Atlas.
Source: NantWorks

Back to Table of contents

Primeur weekly 2012-10-08

The Cloud

ISC Cloud’12 shared new evolution images from HPC and big data in the Cloud ...

Bright Computing to present data aware Cloud bursting to the SLURM User Group ...

Oracle unveils expanded Oracle Cloud Services portfolio ...

Oracle extends Oracle Communications Billing and Revenue Management product family with innovative Oracle Communications Elastic Charging Engine ...

Oracle Enterprise Manager 12c introduces new tools and programmes for partners ...

Fujitsu Cloud solution bolsters Ritsumeikan Asia Pacific University's administrative information system ...

Lending Club selects Oracle ERP Cloud Service to help increase insight and efficiencies ...

Customers live on Oracle Fusion Human Capital Management ...

Oracle continues to extend industry's no. 1 business innovation platform for the enterprise and the Cloud ...

Kwality Dairy selects IBM Cloud to drive supply chain efficiencies ...

Oracle announces ISV integration with Oracle Sales and Marketing Cloud Service ...

Oracle unveils new partner Cloud programmes at Oracle OpenWorld 2012 ...

Fujitsu Cloud solution enhances Kansai University's educational research system platform ...

HP advances software-defined networks with integrated infrastructure, controller and application solutions ...

Oracle announces Oracle Solaris 11.1 at Oracle OpenWorld ...

VMware simplifies compliance for business-critical applications in the Cloud ...

Desktop Grids

OProject@Home has been launched ...

EuroFlash

Altair's latest Compute Manager offers built-in 3D and 2D visualization of high-performance computing simulations ...

Green Brain project to create an autonomous flying robot with a honey bee brain ...

Hi-fi single photons ...

USFlash

Indiana University develops tool to improve NASA polar ice mission ...

Launch of the USA's fastest Genomic Supercomputing Platform reduces cancer genome analysis from months to seconds - One patient every 47 seconds ...

South Australian Research Facility unleashes the Tizard supercomputer ...

Mellanox InfiniBand selected by Fujitsu to accelerate the Australian National University supercomputer ...

Oracle announces Oracle Exadata X3 Database In-Memory Machine ...

Virginia Tech to tackle the Big Data challenges of next-generation sequencing with HokieSpeed ...

Iowa State researchers developing Big Data toolbox to help genome researchers ...

IBM completes acquisition of Texas Memory Systems ...

Brown University awarded $1.5 million for new Big Data tools ...

Cognitech Inc. announces release of industry's fastest mobile and tower supercomputing Forensic Video Workstations ...

Dell Smart Grid Data Management Solution enables utility companies to improve efficiency ...

New Zealand Freight Service provider adopts IBM PureSystems for IT consolidation ...

IBM boosts security, Cloud and analytics capabilities with new Power systems, storage and mainframe technologies ...

Sandia builds Android-based network to study cyber disruptions ...

Sandia gains national recognition for sustainable energy management ...

NSF announces interagency progress on administration's Big Data initiative ...

National Science Foundation awards Rutgers $1.4 million to help create ways to analyze Big Data ...