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Primeur weekly 2019-07-15

Quantum computing

Quantum chemistry on quantum computers ...

Quantum computing: Forschungszentrum Jülich and Google announce research partnership ...

The best of both worlds: how to solve real problems on modern quantum computers ...

Rigetti Computing acquires QxBranch to expand full-stack capabilities ...

Focus on Europe

Pioneer satellites launched ...

Inauguration of the Minho Advanced Computing Centre - MACC - in Portugal ...

e-InfraCentral reports on successful EOSC community event in Tallinn ...

ISC High Performance announces David Keyes as 2020 Programme Chair ...

GCS Centres converge on Frankfurt for ISC19 ...

Gauss Centre for Supercomputing to open 22nd call for large-scale projects ...

Middleware

Argonne team breaks record for Globus Data Movement ...

Hardware

Verne Global joins NVIDIA DGX-Ready Data Center Programme as HPC & AI colocation partner ...

NSF funds Bridges-2 supercomputer at Pittsburgh Supercomputing Center ...

Mellanox Capital extends storage ecosystem with investments in CNEX Labs and Pliops ...

Ohio Supercomputer Center staff leading programmes at PEARC19 conference ...

Tachyum closes $25 million Series A round ...

Vantage Data Centers joins NVIDIA DGX-Ready Data Center Colocation Programme ...

World-class research centre opens in Palo Alto ...

Intel's Pohoiki Beach, a 64-chip neuromorphic system, delivers breakthrough results in research tests ...

Applications

SDSC's Comet supercomputer used to model graphene-water interaction ...

US Naval Research Laboratory 'connects the dots' for quantum networks ...

Deep learning-powered 'DeepEC' helps accurately understand enzyme functions ...

Targeting new treatments for concussions by transforming brain pathology ...

NERSC's Cori system reveals integral role of gluons in proton pressure distribution ...

CMU scientists use XSEDE-allocated resources to simulate improved battery components ...

AI Excellence in Europe: 50 million euro to bring world-class researchers together ...

The Cloud

IBM closes landmark acquisition of Red Hat for $34 billion and defines open, hybrid Cloud future ...

USFlash

Intel unveils new tools in its advanced chip packaging toolbox ...

Targeting new treatments for concussions by transforming brain pathology


Badri Roysam, chair of the University of Houston Department of Electrical and Computer Engineering, is leading a $3.19 million project to create new technology that could provide an unprecedented look at the injured brain and lead to new therapies for concussions. The technology combines multi-spectral imaging and supercomputing, allowing researchers to see the effects of injury, treatments and the body's own healing processes at once. Credit: University of Houston.
11 Jul 2019 Houston - Badri Roysam, chair of the University of Houston Department of Electrical and Computer Engineering, is leading a $3.19 million project to create new technology that could provide an unprecedented look at the injured brain and lead to new therapies for concussions. The technology combines multi-spectral imaging and supercomputing, allowing researchers to see the effects of injury, treatments and the body's own healing processes at once.

"By allowing us to see the effects of the injury, treatments and the body's own healing processes at once, the combination offers unprecedented potential to accelerate investigation and development of next-generation treatments for brain pathologies", stated Badri Roysam, co-principal investigator with John Redell, assistant professor at UTHealth McGovern Medical School. Funded by the National Institute of Neurological Disorders and Stroke (NINDS), the project also includes NINDS scientist Dragan Maric and UH professors Hien Van Nguyen and Saurabh Prasad.

The team is tackling the seemingly familiar concussion, suffered globally by an estimated 42 million people. This mild traumatic brain injury, usually caused by a bump, blow, or jolt to the head, disrupts normal brain function, setting off a cascading series of molecular and cellular alterations that can result in neurological, cognitive and behavioral changes. Concussions have long confounded scientists who face technological limitations that hinder a more comprehensive understanding of the pathological changes triggered by concussion, causing an inability to design effective treatment regimens. Until now.

"We can now go in with eyes wide open whereas before we had only a very incomplete view with insufficient detail", stated Badri Roysam. "The combinations of proteins we can now see are very informative. For each cell, they tell us what kind of brain cell it is, and what is going on with that cell."

Injury to the brain causes immediate changes among all brain cells, severing some connections and potentially causing blood to leak into the brain - where blood is never supposed to be - by breaching the blood/brain barrier. After a concussion, the brain tissue becomes a complex "battleground", said Badri Roysam, with a mix of changes caused by the injury, secondary changes due to drug treatments, side effects and the body's natural processes. Untangling these processes will allow the team to develop new medication "cocktails" of two or more drugs.

"We will present a carefully validated and broadly applicable toolkit with unprecedented potential to accelerate investigation and develop next-generation treatments for brain pathologies", stated Badri Roysam.

Once validated, the new technology can also be applied to strokes, brain cancer and other degenerative diseases of the brain.

Source: University of Houston

Back to Table of contents

Primeur weekly 2019-07-15

Quantum computing

Quantum chemistry on quantum computers ...

Quantum computing: Forschungszentrum Jülich and Google announce research partnership ...

The best of both worlds: how to solve real problems on modern quantum computers ...

Rigetti Computing acquires QxBranch to expand full-stack capabilities ...

Focus on Europe

Pioneer satellites launched ...

Inauguration of the Minho Advanced Computing Centre - MACC - in Portugal ...

e-InfraCentral reports on successful EOSC community event in Tallinn ...

ISC High Performance announces David Keyes as 2020 Programme Chair ...

GCS Centres converge on Frankfurt for ISC19 ...

Gauss Centre for Supercomputing to open 22nd call for large-scale projects ...

Middleware

Argonne team breaks record for Globus Data Movement ...

Hardware

Verne Global joins NVIDIA DGX-Ready Data Center Programme as HPC & AI colocation partner ...

NSF funds Bridges-2 supercomputer at Pittsburgh Supercomputing Center ...

Mellanox Capital extends storage ecosystem with investments in CNEX Labs and Pliops ...

Ohio Supercomputer Center staff leading programmes at PEARC19 conference ...

Tachyum closes $25 million Series A round ...

Vantage Data Centers joins NVIDIA DGX-Ready Data Center Colocation Programme ...

World-class research centre opens in Palo Alto ...

Intel's Pohoiki Beach, a 64-chip neuromorphic system, delivers breakthrough results in research tests ...

Applications

SDSC's Comet supercomputer used to model graphene-water interaction ...

US Naval Research Laboratory 'connects the dots' for quantum networks ...

Deep learning-powered 'DeepEC' helps accurately understand enzyme functions ...

Targeting new treatments for concussions by transforming brain pathology ...

NERSC's Cori system reveals integral role of gluons in proton pressure distribution ...

CMU scientists use XSEDE-allocated resources to simulate improved battery components ...

AI Excellence in Europe: 50 million euro to bring world-class researchers together ...

The Cloud

IBM closes landmark acquisition of Red Hat for $34 billion and defines open, hybrid Cloud future ...

USFlash

Intel unveils new tools in its advanced chip packaging toolbox ...