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Primeur weekly 2016-07-25

Special

SpiNNaker and BrainScaleS neuromorphic systems ready for non-expert use in stochastic inference computing ...

Beyond Moore's Law panelists address business maturity of new technologies, future developments, neuromorphic chip training, and memristors ...

Focus

D-Wave works with its customers Lockheed, Google and Los Alamos to design better quantum software ...

Altair's Bill Nitzberg to present PBS Pro open source license version, PBS Simulator and PBS Cloud Manager ...

Quantum computing

Russian physicists discover a new approach for building quantum computers ...

RMIT researchers make leap in measuring quantum states ...

Focus on Europe

Guiding EU researchers along the last mile to Open Digital Science ...

Digital Humanities and Urban Climate proposals win NLeSC-Lorentz Workshop competition ...

European Horizon 2020 Work Programme update supports competitiveness through open science ...

6th Irish Supercomputer List shows Irish HPC capacity doubles with new no. 1 and three new TOP500-class machines ...

PRACE to look for Peer-Review Officer ...

7th International HPC Summer School took place in Ljubljana, Slovenia ...

Middleware

Inria joins the OpenMP ARB ...

Hardware

Gigabyte announces official release of production-ready Cavium ThunderX-based servers ...

The University of Tokyo selects Mellanox EDR InfiniBand to accelerate its newest supercomputer ...

Smallest hard disk to date writes information atom by atom ...

A mini-antenna for the data processing of tomorrow ...

Hangzhou C-SKY Microsystems joins EEMBC Executive Board ...

Electron spin control: Levitated nanodiamond is research gem ...

The Scripps Research Institute leverages powerful end-to-end DDN storage to help reveal secrets to new medical treatments ...

Applications

MSC Software partners with Italian Campania Region Technological Aerospace District for the development of aeronautical programmes ...

Deloitte Advisory Cyber Risk Services and Cray offer advanced Cyber Reconnaissance and Analytics services ...

Strathclyde mathematician wins prize for research into speeding up stroke diagnosis ...

Underlying molecular networks suggest new targets to combat brain cancer ...

An accelerated pipeline to open materials research ...

Rice wins interdisciplinary Big Data grant ...

Study uses text-mining to improve market intelligence on startups ...

The Cloud

The HNSciCloud Pre-Commercial Procurement tender is out: you can bid now ...

CSC and IBM expand strategic alliance with collaboration utilizing IBM Cloud for z to enable clients' move to Cloud ...

The Scripps Research Institute leverages powerful end-to-end DDN storage to help reveal secrets to new medical treatments

21 Jul 2016 Santa Clara - The Scripps Research Institute (TSRI), one of the world's largest independent organisations focusing on biomedical research, has deployed DataDirect Networks' (DDN) end-to-end data management solutions, including high performance SFA7700X file storage automatically tiered to WOS object storage archive, to support fast analysis and cost-effective retention of research data produced by cryo-electron microscopy (Cryo-EM).

Responsible for creating a "resolution revolution", Cryo-EM enables scientists to create atomic-level, high-resolution 3D molecular models with unprecedented speed and accuracy. In order to accommodate the rapid capture, analysis and long-term retention of this data, DDN end-to-end storage solutions were needed to provide the speed and capacity to manage the rapidly growing, highly valuable data.

TSRI has been at the forefront of Cryo-EM, using advanced microscopes, next-gen digital cameras and sophisticated software pipelines to shed light on new treatments for Alzheimer's, Parkinson's, Lou Gehrig's and Huntington's diseases while identifying new ways to combat HIV, Ebola and Zika. DDN's flexible storage enables TSRI to effectively harness about 30TB of data generated each week by Cryo-EM while scaling an active archive for widespread collaboration and content distribution.

According to Jean-Christophe Ducom, HPC manager, Information Technology Services at TSRI, Cryo-EM has become the biggest producer of data, yielding four times more output than the institute's genomics workflows. "DDN helps us give scientists what they want - unlimited storage capacity and easy access to data that holds the secret to life-saving discoveries", he stated.

TSRI takes advantage of DDN’s SFA7700X, which extracts maximum performance and value from spinning disk and flash storage media, along with the company's WOS high-performance object storage platform to retain thousands of images for research collaboration and model re-analysis. As a result, up to 2PB of instantly accessible storage is on hand to expedite a vast array of Cryo-EM research. Moreover, this dedicated storage foundation also enables TSRI to fully maximize its existing DDN storage with 700TB of capacity for handling other research, including genomics and molecular dynamics.

Thanks to its dedicated Cryo-EM storage and state-of-the-art microscopes from FEI Company, including the powerful Titan Krios and Talos, TSRI is helping scientists respond faster to deadly outbreaks of infectious diseases. For example, the institute has taken advantage of its advanced technology to discover new Ebola-fighting antibodies and identify treatments for Zika.

Previously, using X-ray crystallography, it could take researchers a year or more to determine a protein structure and develop much-needed antibodies. Now, with the ability to rapidly ingest, process, store, analyze and collaborate on massive amounts of data generated by their high-end Cryo-EM, they can do the same in a matter of weeks.

Additionally, scientists in TSRI's Lander lab are using multi-scale, high-resolution 3D imaging to study the structure of dynein, a motor complex important in clearing toxic protein aggregates from neurons. By capturing dynamic snapshots of this protein complex, scientists can pinpoint molecular triggers that lead to neurological diseases.

“Cryo-EM is a complete game-changer in the world of scientific research", stated Gabriel Lander, Ph.D., assistant professor in TSRI's Department of Integrative Structural and Computational Biology. "With our DDN-powered storage, we can accelerate time to discovery while ensuring that scientists have immediate access to decades of vital research."

Source: DataDirect Networks

Back to Table of contents

Primeur weekly 2016-07-25

Special

SpiNNaker and BrainScaleS neuromorphic systems ready for non-expert use in stochastic inference computing ...

Beyond Moore's Law panelists address business maturity of new technologies, future developments, neuromorphic chip training, and memristors ...

Focus

D-Wave works with its customers Lockheed, Google and Los Alamos to design better quantum software ...

Altair's Bill Nitzberg to present PBS Pro open source license version, PBS Simulator and PBS Cloud Manager ...

Quantum computing

Russian physicists discover a new approach for building quantum computers ...

RMIT researchers make leap in measuring quantum states ...

Focus on Europe

Guiding EU researchers along the last mile to Open Digital Science ...

Digital Humanities and Urban Climate proposals win NLeSC-Lorentz Workshop competition ...

European Horizon 2020 Work Programme update supports competitiveness through open science ...

6th Irish Supercomputer List shows Irish HPC capacity doubles with new no. 1 and three new TOP500-class machines ...

PRACE to look for Peer-Review Officer ...

7th International HPC Summer School took place in Ljubljana, Slovenia ...

Middleware

Inria joins the OpenMP ARB ...

Hardware

Gigabyte announces official release of production-ready Cavium ThunderX-based servers ...

The University of Tokyo selects Mellanox EDR InfiniBand to accelerate its newest supercomputer ...

Smallest hard disk to date writes information atom by atom ...

A mini-antenna for the data processing of tomorrow ...

Hangzhou C-SKY Microsystems joins EEMBC Executive Board ...

Electron spin control: Levitated nanodiamond is research gem ...

The Scripps Research Institute leverages powerful end-to-end DDN storage to help reveal secrets to new medical treatments ...

Applications

MSC Software partners with Italian Campania Region Technological Aerospace District for the development of aeronautical programmes ...

Deloitte Advisory Cyber Risk Services and Cray offer advanced Cyber Reconnaissance and Analytics services ...

Strathclyde mathematician wins prize for research into speeding up stroke diagnosis ...

Underlying molecular networks suggest new targets to combat brain cancer ...

An accelerated pipeline to open materials research ...

Rice wins interdisciplinary Big Data grant ...

Study uses text-mining to improve market intelligence on startups ...

The Cloud

The HNSciCloud Pre-Commercial Procurement tender is out: you can bid now ...

CSC and IBM expand strategic alliance with collaboration utilizing IBM Cloud for z to enable clients' move to Cloud ...