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Primeur weekly 2014-07-14

Special

Six European exascale projects are dealing with the hardware and software challenges in exascale ...

The Cloud

Registration opens for ISC Cloud and ISC Big Data Conferences ...

IBM announces $3 billion research initiative to tackle chip grand challenges for Cloud and Big Data systems ...

'Melbourne Shuffle' secures data in the Cloud ...

Cloud Pharmaceuticals granted 1 million hours of supercomputer time to target orphan diseases including malaria ...

EuroFlash

GRNET signed contract for the development of Greece's National HPC infrastructure ...

Speeding up data storage by a thousand times with 'spin current' ...

IBM, Astron and the University of Groningen launch exascale computing centre to address Big Data challenges ...

Stronger data security ...

New supercomputer accelerates pace of health research across North of England ...

Commission urges governments to embrace potential of Big Data ...

USFlash

InfoComm issues Call for Presenters for ISE 2015 ...

Cray awarded $174 million supercomputer contract from the National Nuclear Security Administration ...

Small but plentiful: How the faintest galaxies illuminated the early universe ...

University of Illinois study advances limits for ultrafast nano-devices ...

SDSC's new 'SeedMe' resource invites researchers to rapidly share results ...

SDSC's KC Claffy receives annual IEEE Internet Award ...

SDSC assists researchers in novel wildlife tracking project ...

MIT researchers unveil experimental 36-core chip ...

Researchers use NSF-supported Stampede supercomputer to improve catalysts for conversion ...

NSF-funded supercomputer helps researchers interpret genomes ...

Terascala expands executive team ...

LANL, Sandia, Cray set to build next generation NNSA supercomputer ...

ICBA selects Dell solutions to help study water resource issues in the MENA region ...

Research could lead to dramatic energy savings at data farms ...

Cloud Pharmaceuticals granted 1 million hours of supercomputer time to target orphan diseases including malaria

14 Jul 2014 Research Triangle Park - Cloud Pharmaceuticals Inc., a therapeutics company focused on Cloud-based drug design and development, has expanded its drug design and development programme. The company has been granted supercomputing time at Argonne National Laboratory to design inhibitors of multiple parasitic targets.

Through a discretionary allocation of 1 million core-hours at the Argonne Leadership Computing Facility (ALCF), researchers at Cloud Pharmaceuticals will use Mira, a 10-petaflops IBM Blue Gene/Q supercomputer to investigate inhibitors of the dihydrofolate reductase enzyme, or DHFR, from multiple sources. The purpose is to identify leading drug candidates for broad-impact, anti-parasitic therapeutics targeting several orphan diseases including malaria. The results will be published to the scientific community and general public. Preclinical development is expected to follow.

"Very often, the same protein will mutate and cause different types of illness or disease. Targeting this protein at a molecular level helps to identify a more effective treatment protocol", stated Ed Addison, CEO of Cloud Pharmaceuticals.

Cloud Pharmaceuticals is using a highly parallel, quantum mechanics/molecular mechanics (QM/MM) computational chemistry algorithm and bioinformatics tools to increase the accuracy of the algorithms used in drug discovery. Cloud Pharmaceuticals also uses its Inverse Design in silico drug design technology and applies novel artificial intelligence algorithms to search through large portions of molecular space to identify the best drug candidates.
Source: Cloud Pharmaceuticals

Back to Table of contents

Primeur weekly 2014-07-14

Special

Six European exascale projects are dealing with the hardware and software challenges in exascale ...

The Cloud

Registration opens for ISC Cloud and ISC Big Data Conferences ...

IBM announces $3 billion research initiative to tackle chip grand challenges for Cloud and Big Data systems ...

'Melbourne Shuffle' secures data in the Cloud ...

Cloud Pharmaceuticals granted 1 million hours of supercomputer time to target orphan diseases including malaria ...

EuroFlash

GRNET signed contract for the development of Greece's National HPC infrastructure ...

Speeding up data storage by a thousand times with 'spin current' ...

IBM, Astron and the University of Groningen launch exascale computing centre to address Big Data challenges ...

Stronger data security ...

New supercomputer accelerates pace of health research across North of England ...

Commission urges governments to embrace potential of Big Data ...

USFlash

InfoComm issues Call for Presenters for ISE 2015 ...

Cray awarded $174 million supercomputer contract from the National Nuclear Security Administration ...

Small but plentiful: How the faintest galaxies illuminated the early universe ...

University of Illinois study advances limits for ultrafast nano-devices ...

SDSC's new 'SeedMe' resource invites researchers to rapidly share results ...

SDSC's KC Claffy receives annual IEEE Internet Award ...

SDSC assists researchers in novel wildlife tracking project ...

MIT researchers unveil experimental 36-core chip ...

Researchers use NSF-supported Stampede supercomputer to improve catalysts for conversion ...

NSF-funded supercomputer helps researchers interpret genomes ...

Terascala expands executive team ...

LANL, Sandia, Cray set to build next generation NNSA supercomputer ...

ICBA selects Dell solutions to help study water resource issues in the MENA region ...

Research could lead to dramatic energy savings at data farms ...