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Primeur weekly 2011-07-18

The Cloud

Rutgers-led experts assemble globe-spanning supercomputer Cloud ...

IBM debuts Cloud-based analytics suite to help companies boost marketing results ...

HP accelerates customers' path to open, hybrid Cloud ...

IBM expands business in Japan with new Cloud data centres ...

VMware unveils VMware vSphere 5 and comprehensive Cloud infrastructure suite ...

Panaya reaches 2,000 ERP systems milestone ...

VMware introduces VMware vSphere Storage Appliance to further simplify IT for small and midsized businesses ...

ET Water celebrates smart irrigation month with the launch of the GNOME Smart Irrigation Calculator ...

From end-user to data centre: Cisco enhances Cloud computing performance, efficiency and security ...

Desktop Grids

Version 4.2.4 of OurGrid middleware released ...

XtremWeb-HEP 7.5.0 released ...

EuroFlash

Lomonosov supercomputer sets world record for performance on Graph500 benchmark ...

European Commission to organize Information Day on Cloud Computing, Internet of Services and Advanced Software Engineering ...

Bright Cluster Manager selected by Freie Universitaet Berlin to manage new Dell-based HPC system ...

Eurotech to receive 4 million euro order from Selex Elsag for Aurora HPC for cyber security applications ...

Medicsight and Ziooft partner in U.S. to offer computer-aided detection with supercomputing functional analytics ...

Imec achieves breakthroughs in enabling future DRAM and RRAM ...

USFlash

IBM Power Systems running Linux outperform competition on standard benchmarks ...

Drexel University chose advanced HPC and Bright Cluster Manager to help unravel the mysteries of the Universe and the world of molecular dynamics ...

Moving data at the speed of science: Berkeley Lab lays foundation for 100 Gbps prototype network ...

Scientists model physics of a key dark-energy probe ...

SDSC visualizations win 'OASCR' Awards at SciDAC 2011 ...

SDSC's Trestles provides rapid turnaround and enhanced performance for diverse researchers ...

Sandia's 'cooler' technology offers fundamental breakthrough in heat transfer ...

Changsha National Supercomputing Center inaugurated ...

Oracle introduces Oracle Exadata Storage Expansion Rack ...

University of Virginia's Olivier Pfister accomplishes breakthrough toward quantum computing ...

GNS Healthcare collaborates with NCI in new approach to lung cancer: supercomputer analysis to aid in matching targeted drugs to patients ...

Wolfram Research announces gridMathematica 8: Adding the power of CUDA over the Grid ...

UC Irvine study points to new approach to influenza's antiviral resistance ...

basysKom, Codero, Gluster and Nixu Open join The Linux Foundation ...

Stanford engineers build a nanoscale device for brain-inspired computing ...

NVIDIA names Stanford University a CUDA Center of Excellence ...

NIST prototype 'optics table on a chip' places microwave photon in 2 colours at once ...

GNS Healthcare collaborates with NCI in new approach to lung cancer: supercomputer analysis to aid in matching targeted drugs to patients

12 Jul 2011 Cambridge - GNS Healthcare Inc. (GNS) is collaborating with the National Cancer Institute (NCI) to accelerate lung cancer research with a supercomputing platform that can rapidly uncover cause-and-effect mechanisms hidden in huge data sets assembled from imaging, genetics, pathology, and other areas. The results could help predict which patients will respond to a given treatment.

GNS will analyze NCI data from the laboratory of Terry van Dyke, Ph.D., Director of the Center for Advanced Preclinical Research (CAPR) at NCI. These data were generated from genetically modified mouse models of non-small cell lung cancer (NSCLC).

This collaboration will utilize GNS's supercomputer-driven REFS platform to build computer models of NSCLC in a hypothesis-free, unbiased manner that will be simulated to identify key molecular mechanisms of NSCLC. The goal is to identify biomarkers and biological mechanisms that will lead to better matching of drugs to patients and new effective drugs in NSCLC.

“GNS is excited to be deploying our supercomputer-driven REFS platform to enable the maximal extraction of actionable knowledge from the rich lung cancer datasets generated by the NCI", stated GNS Executive Vice President and Co-Founder Dr. Iya Khalil. "Combined with the expertise of our NCI colleagues in lung cancer biology and in designing powerful experiments to uncover its key mechanisms, we are creating the opportunity to provide better outcomes for lung cancer patients."

The data utilized in the collaboration will include data from the experimental assessment of transcriptomic and MRI data relating to NSCLC induction, regression and combination drug treatments. Starting from this data, GNS will utilize the REFS platform to reverse-engineer network models from the data that connect drug doses to transcriptional and imaging measurement networks to endpoints. The results from millions of in silico simulations of these models will provide unique insights into the fundamental mechanisms of NSCLC and its response to drug treatments, enabling the development of more effective treatments for NSCLC.

The initial phase of this project is also intended to help GNS and NCI develop standards for the exchange of data to conduct future collaborations in other relevant mouse model systems. From this starting point, the groups envision the possibility of a combined experimental and computational work flow aimed at rapidly enabling the generation of hypotheses, testing these hypothesis in silico and in vivo, generating new confirmatory data, and rapidly cycling back to additional computational modeling, with the goal of accelerating the conversion of knowledge into new clinical options for cancer patients.
Source: GNS Healthcare

Back to Table of contents

Primeur weekly 2011-07-18

The Cloud

Rutgers-led experts assemble globe-spanning supercomputer Cloud ...

IBM debuts Cloud-based analytics suite to help companies boost marketing results ...

HP accelerates customers' path to open, hybrid Cloud ...

IBM expands business in Japan with new Cloud data centres ...

VMware unveils VMware vSphere 5 and comprehensive Cloud infrastructure suite ...

Panaya reaches 2,000 ERP systems milestone ...

VMware introduces VMware vSphere Storage Appliance to further simplify IT for small and midsized businesses ...

ET Water celebrates smart irrigation month with the launch of the GNOME Smart Irrigation Calculator ...

From end-user to data centre: Cisco enhances Cloud computing performance, efficiency and security ...

Desktop Grids

Version 4.2.4 of OurGrid middleware released ...

XtremWeb-HEP 7.5.0 released ...

EuroFlash

Lomonosov supercomputer sets world record for performance on Graph500 benchmark ...

European Commission to organize Information Day on Cloud Computing, Internet of Services and Advanced Software Engineering ...

Bright Cluster Manager selected by Freie Universitaet Berlin to manage new Dell-based HPC system ...

Eurotech to receive 4 million euro order from Selex Elsag for Aurora HPC for cyber security applications ...

Medicsight and Ziooft partner in U.S. to offer computer-aided detection with supercomputing functional analytics ...

Imec achieves breakthroughs in enabling future DRAM and RRAM ...

USFlash

IBM Power Systems running Linux outperform competition on standard benchmarks ...

Drexel University chose advanced HPC and Bright Cluster Manager to help unravel the mysteries of the Universe and the world of molecular dynamics ...

Moving data at the speed of science: Berkeley Lab lays foundation for 100 Gbps prototype network ...

Scientists model physics of a key dark-energy probe ...

SDSC visualizations win 'OASCR' Awards at SciDAC 2011 ...

SDSC's Trestles provides rapid turnaround and enhanced performance for diverse researchers ...

Sandia's 'cooler' technology offers fundamental breakthrough in heat transfer ...

Changsha National Supercomputing Center inaugurated ...

Oracle introduces Oracle Exadata Storage Expansion Rack ...

University of Virginia's Olivier Pfister accomplishes breakthrough toward quantum computing ...

GNS Healthcare collaborates with NCI in new approach to lung cancer: supercomputer analysis to aid in matching targeted drugs to patients ...

Wolfram Research announces gridMathematica 8: Adding the power of CUDA over the Grid ...

UC Irvine study points to new approach to influenza's antiviral resistance ...

basysKom, Codero, Gluster and Nixu Open join The Linux Foundation ...

Stanford engineers build a nanoscale device for brain-inspired computing ...

NVIDIA names Stanford University a CUDA Center of Excellence ...

NIST prototype 'optics table on a chip' places microwave photon in 2 colours at once ...