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Primeur weekly 2015-05-11

Special

German Tier 2 supercomputer centres should form a collaboration network for High-Performance Computing ...

The Cloud

ANSYS 16.1 delivers enterprise simulation On The Cloud ...

IBM Watson establishes hybrid Cloud capabilities to accelerate new insights for the enterprise ...

HP and SAP accelerate journey to SAP S/4HANA on HP Helion managed Cloud ...

Industrial virtual factory lowers costs and reduces emissions ...

HP makes performance and load testing solutions available on the Microsoft Azure Marketplace ...

EuroFlash

High Performance computing element of the European Commission's new Digital Single Market Strategy for Europe ...

Biologists are increasingly becoming data scientists ...

Announcing the Hans Meuer Award winning Research Paper ...

ADVA Optical Networking launches ConnectGuard for ultimate data protection ...

German researchers use IBM Big Data solution to manage world's largest trove of climate data ...

15 million euro boost for European astronomy ...

USFlash

Gartner names CoolIT Systems a Cool Vendor in Data Center Management, Power and Cooling Report ...

University of Arkansas acquires new supercomputer for research support ...

OpenMP 4.0 examples published ...

Cray names Nick Gorga to Vice President of Asia Pacific Sales ...

Cray reports first quarter financial results ...

Cray Urika-XA system wins Best of Show Award at Bio-IT World ...

Purdue's eighth supercomputing cluster in eight years not quite 'minute' Rice, but built in a day ...

UT Austin researchers use supercomputing to assess the impact of climate change on the country's growing season ...

IBM Watson Health, Epic and Mayo Clinic to unlock new insights from electronic health records ...

Scientists get ultra-fast and robust network across the Atlantic Ocean ...

Nepal disaster relief efforts to be aided by glacier researchers ...

Clinicians tap Watson to accelerate DNA analysis and inform personalized treatment options for patients ...

New chip architecture may provide foundation for quantum computer ...

The next step in DNA computing: GPS mapping? ...

IBM unveils Power Systems solutions to support SAP HANA ...

Biologists are increasingly becoming data scientists

6 May 2015 Wageningen - Biology is rapidly acquiring the character of a data science. Billions of data points on genes, proteins and other molecules are compiled in large files and systematically studied. This should lead to more knowledge and understanding about living organisms, including crops and livestock that are the basis of food security for the world population. These are some of points raised by Dick de Ridder in his inaugural address upon accepting the post of Professor of Bioinformatics at Wageningen University on 30 April 2015.

In his address, entitled "Biology as Data Science - Zen and the Art of Bioinformatics", Dick de Ridder discussed the unstoppable growth of data on genomes, proteins and cells, which far outstrips Moore's Law on the falling costs of micro-electronic processing power. Between 1990 and 2003, unravelling the human genome - with more than three billion building blocks - cost approximately $ 2.7 billion, but in 2014 the costs for unravelling the same genome were barely $ 4,000. The gradual reduction in cost made a huge increase in the amount of data possible, allowing scientists to read the genomes of tens of thousands of organisms. Mapping out the complex tomato genome took an international consortium five years to accomplish, but today researchers can read the genomes of 150 different tomatoes in one year. "The expectation is that this year we will be able to read a million billion, or 25 petabases of DNA, worldwide", calculated Dick De Ridder.

All this data from analyses of the properties, structure and functions of tens of thousands of molecules in cells, is stored in enormous databases. This unimaginable amount of data is also referred to as 'Big Data'. Dealing with Big Data requires a different approach. "It is the art of the bioinformatician", stated Dick de Ridder, "to establish new biological hypotheses on the basis of terabytes of original data. Biologists currently outsource much of their data analysis to bioinformaticians, but I expect that more and more researchers will make predictions from behind their computers, which will then be validated in outsourced experiments."

In order to move from data to understanding, Dick de Ridder envisions a procedure with several steps, in which "the computer scientist needs to move in the direction of the biologist. In a sense, this movement is from a reductionist to a holistic approach. Processing the biological data at the deepest level, such as DNA base pairs, therefore only makes sense if this analysis can be used to build models of biological processes and if the resulting predictions can be tested. That can yield fundamental insights", concluded Dick de Ridder. "Conversely, biologists can no longer allow themselves to accept predictions of models without understanding the data analysis."

The Bioinformatics Group at Wageningen University was founded in 2002. The first Professor of Bioinformatics was Jack Leunissen. He provided inspiring leadership for the group until his untimely death in mid-May of 2012.
Source: Wageningen University and Research Centre

Back to Table of contents

Primeur weekly 2015-05-11

Special

German Tier 2 supercomputer centres should form a collaboration network for High-Performance Computing ...

The Cloud

ANSYS 16.1 delivers enterprise simulation On The Cloud ...

IBM Watson establishes hybrid Cloud capabilities to accelerate new insights for the enterprise ...

HP and SAP accelerate journey to SAP S/4HANA on HP Helion managed Cloud ...

Industrial virtual factory lowers costs and reduces emissions ...

HP makes performance and load testing solutions available on the Microsoft Azure Marketplace ...

EuroFlash

High Performance computing element of the European Commission's new Digital Single Market Strategy for Europe ...

Biologists are increasingly becoming data scientists ...

Announcing the Hans Meuer Award winning Research Paper ...

ADVA Optical Networking launches ConnectGuard for ultimate data protection ...

German researchers use IBM Big Data solution to manage world's largest trove of climate data ...

15 million euro boost for European astronomy ...

USFlash

Gartner names CoolIT Systems a Cool Vendor in Data Center Management, Power and Cooling Report ...

University of Arkansas acquires new supercomputer for research support ...

OpenMP 4.0 examples published ...

Cray names Nick Gorga to Vice President of Asia Pacific Sales ...

Cray reports first quarter financial results ...

Cray Urika-XA system wins Best of Show Award at Bio-IT World ...

Purdue's eighth supercomputing cluster in eight years not quite 'minute' Rice, but built in a day ...

UT Austin researchers use supercomputing to assess the impact of climate change on the country's growing season ...

IBM Watson Health, Epic and Mayo Clinic to unlock new insights from electronic health records ...

Scientists get ultra-fast and robust network across the Atlantic Ocean ...

Nepal disaster relief efforts to be aided by glacier researchers ...

Clinicians tap Watson to accelerate DNA analysis and inform personalized treatment options for patients ...

New chip architecture may provide foundation for quantum computer ...

The next step in DNA computing: GPS mapping? ...

IBM unveils Power Systems solutions to support SAP HANA ...