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Primeur weekly 2011-05-16

EuroFlash

Jülich makes a crutial step towards Exascale computer with the introduction of hybrid clusters using Tesla 20-series GPU's ...

Cray signs contract to upgrade and expand the Cray XE6 supercomputer at the University of Edinburgh ...

Cray reports first quarter 2011 financial results ...

Electromechanics also operates at the nanoscale ...

ICM selects IBM to fuel national science ...

USFlash

Carbon, carbon, everywhere; But not from the Big Bang ...

Cisco Networking Solutions increase security and mobility with Cloud services for branch offices ...

Xerox and Cisco to form alliance to deliver Cloud services; Combine network intelligence and print management ...

Cray and Sandia establish a Supercomputing Institute for Learning and Knowledge Systems ...

EMC Isilon delivers world's largest single file system for big data ...

EMC and Box deliver enterprise content management mobility through the Cloud ...

EMC enables service providers to accelerate customers' journey to Cloud computing ...

EMC delivers "Cloud to Ground" root-cause analysis for data centres ...

EMC delivers Hadoop 'big data' analytics to the enterprise ...

New EMC Ionix UIM software simplifies Cloud infrastructure management ...

EMC connects VNX to the Cloud with new Cloud Tiering Appliance ...

Graphene optical modulators could lead to ultrafast communications ...

HP puts data storage on a diet and guarantees capacity reduction ...

HP launches high-performance FlexNetwork solutions for video and mobile computing ...

HP readies enterprises for the future with FlexNetwork architecture ...

IBM delivers technology to help clients protect and retain "Big Data" ...

Primerica selects new IBM zEnterprise mainframe server for smarter infrastructure ...

Proton dripping tests a fundamental force in nature ...

Raritan's data centre energy management software gets a new dashboard with forecasting tools and gauges to track and visualize key energy metrics ...

Red Hat revolutionizes the private and hybrid Cloud market ...

Rice doubles supercomputing capacity ...

Student, 16, invents new drug cocktail to fight cystic fibrosis, wins Canadian biotech challenge ...

Student, 16, invents new drug cocktail to fight cystic fibrosis, wins Canadian biotech challenge

10 May 2011 Toronto - While many 16-year-olds are content with PlayStation, Toronto-area student Marshall Zhang used the Canadian SCINET supercomputing network to invent a new drug cocktail which could one day help treat cystic fibrosis. The Grade 11 student at Bayview Secondary School in Richmond Hill so impressed eight eminent scientists at the National Research Council of Canada laboratories in Ottawa they awarded him first prize in the 2011 Sanofi-Aventis BioTalent Challenge.

Jonathan Khouzam, Simon Leclerc, Francis Marcogliese, all 19, of Montreal's CÉGEP Collège Jean-de-Brébeuf, won the 2nd place prize for finding a way to produce a great sorbet without geletin, potentially opening a large new vegetarian market for the popular frozen dessert. Geletin is derived from the skin and bones of animals.

First and second place winners receive $5,000 and $4,000 respectively. The trio from Montreal also won a special $1,000 prize for the project deemed by the judges to have the greatest commercial potential.

Marshall Zhang and the Montreal team will compete against US and Australian teams at the International BioGENEius Challenge in Washington, DC, June 27, held in conjunction with the Biotechnology Industry Organization's (BIO) Annual International Convention.

The other top prizes were collected by:

  • 3rd place ($3,000): Shannon Watson, 18, a Grade 12 student at Ottawa's Cantebury High School, who identified bacteria in a pro-biotic fermented milk product from Zambia that inhibit the growth of antibiotic-resistant bacteria;
  • 4th place ($2,000): Yasamin Mahjoub, 16, a Grade 11 student at Sir Winston Churchill High School, Calgary, who showed that hormones produced by pregnant women protect neurons from the effects of iron accumulation in the brain, suggesting a new line of inquiry into the causes and treatment of multiple sclerosis; and
  • 5th place ($1,000): Siyuan Cheng, 18, a Grade 12 student at Fort Richmond Collegiate, Winnipeg, who combined the standard drug treatment for leukaemia with a lung cancer drug to greatly increase the numbers of leukemia cells being killed.

Remarkable students from every province presented the judges with 14 truly cutting-edge biotechnology projects related to health, agriculture and the environment. All were previous prize-winners at regional SABC competitions held across Canada in April.

All 13 to 19 years old and enrolled in Grades 9 through 12, the students were mentored by university professors and others who volunteer their expertise and many hours over several months each year to assist these young researchers.

Grade 11 student Marshall Zhang impressed many experts when he used the Canadian SCINET supercomputing network to discover a new and potentially effective drug cocktail to treat cystic fibrosis. The results demonstrated the usefulness of computer-based approaches to discover drug-like compounds.

"Marshall's findings show that computational methods can drive the discovery of compounds that may offer effective treatment for cystic fibrosis (CF)", stated his project mentor Dr. Christine Bear, a researcher at the Hospital for Sick Children's Research Institute.

CF is a common genetic disease where the lungs' normal protective coating of thin mucus becomes thick and sticky - an inviting environment for serious, sometimes fatal bacterial infections. A genetic mutation is responsible for most cases of CF. Leading research currently in clinical trials suggests that specific drugs may help correct this defect.

At Dr. Bear's lab at Sick Kids, Marshall Zhang used sophisticated SCINET computer modelling to investigate what these drugs might be doing to 'correct' the genetic defect at the molecular level. On the computer, he identified how two drugs each interacted with one specific part of the mutant protein. He then proved his 'virtual' findings were correct using living cells in culture.

Marshall Zhang correctly suspected that using two drugs together might prove more effective because they interacted with different parts of the mutant protein. "The cells treated with the two drugs were functioning as if they were the cells of healthy individuals", stated Marshall.

"The thrill of knowing that I was on the forefront of current knowledge was absolutely the best thing about my experience", stated Marshall Zhang, adding that the lab work and "getting a taste of real research has definitely driven me towards pursuing science in the future".

"I think that Marshall has tremendous potential to be a scientist in the future because of his intelligence, motivation and determination", added Dr. Bear.

Source: Bioscience Education Canada

Back to Table of contents

Primeur weekly 2011-05-16

EuroFlash

Jülich makes a crutial step towards Exascale computer with the introduction of hybrid clusters using Tesla 20-series GPU's ...

Cray signs contract to upgrade and expand the Cray XE6 supercomputer at the University of Edinburgh ...

Cray reports first quarter 2011 financial results ...

Electromechanics also operates at the nanoscale ...

ICM selects IBM to fuel national science ...

USFlash

Carbon, carbon, everywhere; But not from the Big Bang ...

Cisco Networking Solutions increase security and mobility with Cloud services for branch offices ...

Xerox and Cisco to form alliance to deliver Cloud services; Combine network intelligence and print management ...

Cray and Sandia establish a Supercomputing Institute for Learning and Knowledge Systems ...

EMC Isilon delivers world's largest single file system for big data ...

EMC and Box deliver enterprise content management mobility through the Cloud ...

EMC enables service providers to accelerate customers' journey to Cloud computing ...

EMC delivers "Cloud to Ground" root-cause analysis for data centres ...

EMC delivers Hadoop 'big data' analytics to the enterprise ...

New EMC Ionix UIM software simplifies Cloud infrastructure management ...

EMC connects VNX to the Cloud with new Cloud Tiering Appliance ...

Graphene optical modulators could lead to ultrafast communications ...

HP puts data storage on a diet and guarantees capacity reduction ...

HP launches high-performance FlexNetwork solutions for video and mobile computing ...

HP readies enterprises for the future with FlexNetwork architecture ...

IBM delivers technology to help clients protect and retain "Big Data" ...

Primerica selects new IBM zEnterprise mainframe server for smarter infrastructure ...

Proton dripping tests a fundamental force in nature ...

Raritan's data centre energy management software gets a new dashboard with forecasting tools and gauges to track and visualize key energy metrics ...

Red Hat revolutionizes the private and hybrid Cloud market ...

Rice doubles supercomputing capacity ...

Student, 16, invents new drug cocktail to fight cystic fibrosis, wins Canadian biotech challenge ...