The multi-national research team uses a recently upgraded cluster system based on 2ndGeneration Intel Xeon Scalable processors, which has been deployed by RSC Group, a Russian solution provider for high-performance computing.
The international project aims to develop medicine for diagnostics and therapy against the coronavirus contagious disease that became the cause of the global pandemic. Finding treatments to prevent and mitigate the negative impact of COVID-19 is the highest priority in the worldwide scientific community now. The international and multidisciplinary project takes advantage of the latest advances in experimental physics, chemistry, and biology to investigate the life cycle of the virus and to target specifically its specific proteins. Sophisticated simulation methods require supercomputing power to study all details of the interaction between the Spike-protein on the coronavirus surface and the human protein ACE2 which is known to be the entry point for SARS and SARS-2 coronaviruses. It will help to complete all research stages within a limited amount of time.
"Rapid global spread of COVID-19 coronavirus infection pandemic has shown that there are no clear global emergency response plans against threats to humankind caused by new viruses. One of the obvious shortcomings is the lack of technologies for the quick development of medicines for diagnostics and therapy. We all have different competencies, knowledge, skills and resources. Our geographically distributed team includes virologists, biologists, chemists, mathematicians and physical scientists. The international cooperation is extremely important to achieve quick progress and rapidly react to the ever-changing situation with global coronavirus pandemic. We hope that our research will actually help to fight the spread of such infections", explained Anna Kichkailo, Head of Laboratory for Digital Controlled Drugs and Theranostics at the Krasnoyarsk Federal Science Center of Russian Academy of Sciences.
The international team consists of: