Back to Table of contents

Primeur weekly 2018-04-23

Special

Commissioner Mariya Gabriel sees a growing sense of community in EuroHPC exascale initiative ...

Focus

ETAIS and eInfraCentral: a national and a European approach for offering e-Infrastructure services ...

Exascale supercomputing

The Exascale Computing Project (ECP) appoints GE's Brunon (Dave) Kepczynski as Industry Council Chair ...

Quantum computing

Novel thermal phases of topological quantum matter in the lab ...

Focus on Europe

ISC STEM Student Day opens for sign-up, includes free HPC & Machine Learning tutorial ...

Key role for University of Bristol in new supercomputer collaboration ...

e-IRG Open Workshop to focus on EuroHPC and development of e-Infrastructures in South-Eastern European (SEE) and Eastern-Mediterranean (EM) region ...

The JUWELS supercomputer in Juelich ...

KTH Sweden to organize PDC Summer School - Introduction to High Performance Computing ...

Hardware

Memorandum of Understanding on future international collaboration projects ...

New direct link from South Africa enables global science ...

Integrating optical components into existing chip designs ...

Russian RSC Group deployed the world first 100% hot water liquid cooled supercomputer at Joint Institute for Nuclear Research ...

DDN Storage builds major new engineering facility in Colorado focused on solving AI, Cloud and large-scale enterprise data challenges ...

Cray debuts AMD EPYC processors in supercomputer product line ...

Fujitsu upgrades RIKEN's AI research computer RAIDEN; reaches top tier of processing performance in Japan ...

Fujitsu launches new GS21 mainframe models supporting next-generation mission-critical systems ...

Applications

EMBO Practical Course on Integrative modelling of biomolecular interactions at Barcelona Supercomputing Center ...

Your digital twin: closer than you think - How computer models can predict health and help to prevent and cure diseases ...

From insulator to conductor in a flash ...

Oregon scientists decipher the magma bodies under Yellowstone ...

Some superconductors can also carry currents of 'spin' ...

Improving citizen science and big data analysis ...

Diamond-like carbon is formed differently to what was believed - machine learning enables development of new model ...

AI projected to replace thousands of banking jobs ...

The Cloud

UTSA Open Cloud Institute supports Cloud research & launches certificate programme ...

Your digital twin: closer than you think - How computer models can predict health and help to prevent and cure diseases


Virtual heart. Credit: CompBioMed.
19 Apr 2018 Amsterdam - Imagine your doctor has a digital copy of you stored in his or her computer. Your digital twin is like a volunteer that is always there for you, on which treatment of any disease you may have can be tested. This clone can breathe and walk, but can also break a leg or develop cardiovascular diseases. All of this takes place in the computer. It might sounds futuristic, but researchers around the world, including at the University of Amsterdam (UvA), are working to turn this into a reality. A short film about the "Virtual Physiological Humans" project was released this Spring.

As early as the 1980s, we had a good understanding of the electrical, chemical and mechanical properties of cardiac muscle cells and had computer models of these cells. Nowadays, complete virtual hearts are beating inside the computer. We also have highly realistic computer models of many other organs, including the skeleton, muscles, lungs, blood vessels, etc.

Developments are taking place at breakneck speed. The first FDA accreditation in 2016 was an important milestone, as it showed that computer models can be useful in the treatment of patients. Powerful computers such as Cartesius, the national supercomputer at SURFsara in Amsterdam, the Netherlands, facilitate to compute a virtual heart or a virtual artery down to the last detail. Accordingly, the first complete digital clone is expected to become a reality in the next five to ten years.

In addition to supercomputers, medical scanners are key to developing your digital twin. What began with Antonie van Leeuwenhoek's invention of the microscope, revealing the invisible world of cells and micro-organisms, has led to modern-day techniques that create advanced images of organs and processes. In this way, scientists are able not just to build a virtual physiological human being, but to shape it completely in accordance with the specific characteristics of a given individual.

It is expected that this digital copy will contribute significantly to personalised medicine, with fully tailor-made treatments for diseases, rather than treatments based on what is best on average for a large group of patients. Digital twins can also be used forin silicoclinical trials, in which computer models test medication. The UvA, for instance, is cooperating with the Amsterdam Medical Centre (AMC) on anin silicoclinical trial for the treatment of acute ischemic stroke. This should lead to faster and more efficient introduction of new medication, as well as a reduction in the use of laboratory animals in medical research.

A worldwide group of universities, hospitals and companies are working on the development of the digital twin, with research groups focusing on smaller parts of the body. Much of this research is taking place as part of the European CompBioMed project, in which researchers of the UvA's Computational Science Lab are participating. Prof. Alfons Hoekstra is working on virtual arteries and (super)computing techniques that enable simulations. Prof. Peter Sloot is working on models of the immune system, which have applications in such areas as HIV and diabetes. The Computational Science Lab in Amsterdam is also studying the interaction between the digital twin and its environment.

The research consortium CompBioMed has produced a ten-minute film about the development of the virtual human. It was shown at a number of Science film festivals and has been available on YouTube since last month. In related interviews, some of the key researchers, including Prof. Hoekstra, give an update on developments around digital twines and share their expectations of the future.

Source: University of Amsterdam

Back to Table of contents

Primeur weekly 2018-04-23

Special

Commissioner Mariya Gabriel sees a growing sense of community in EuroHPC exascale initiative ...

Focus

ETAIS and eInfraCentral: a national and a European approach for offering e-Infrastructure services ...

Exascale supercomputing

The Exascale Computing Project (ECP) appoints GE's Brunon (Dave) Kepczynski as Industry Council Chair ...

Quantum computing

Novel thermal phases of topological quantum matter in the lab ...

Focus on Europe

ISC STEM Student Day opens for sign-up, includes free HPC & Machine Learning tutorial ...

Key role for University of Bristol in new supercomputer collaboration ...

e-IRG Open Workshop to focus on EuroHPC and development of e-Infrastructures in South-Eastern European (SEE) and Eastern-Mediterranean (EM) region ...

The JUWELS supercomputer in Juelich ...

KTH Sweden to organize PDC Summer School - Introduction to High Performance Computing ...

Hardware

Memorandum of Understanding on future international collaboration projects ...

New direct link from South Africa enables global science ...

Integrating optical components into existing chip designs ...

Russian RSC Group deployed the world first 100% hot water liquid cooled supercomputer at Joint Institute for Nuclear Research ...

DDN Storage builds major new engineering facility in Colorado focused on solving AI, Cloud and large-scale enterprise data challenges ...

Cray debuts AMD EPYC processors in supercomputer product line ...

Fujitsu upgrades RIKEN's AI research computer RAIDEN; reaches top tier of processing performance in Japan ...

Fujitsu launches new GS21 mainframe models supporting next-generation mission-critical systems ...

Applications

EMBO Practical Course on Integrative modelling of biomolecular interactions at Barcelona Supercomputing Center ...

Your digital twin: closer than you think - How computer models can predict health and help to prevent and cure diseases ...

From insulator to conductor in a flash ...

Oregon scientists decipher the magma bodies under Yellowstone ...

Some superconductors can also carry currents of 'spin' ...

Improving citizen science and big data analysis ...

Diamond-like carbon is formed differently to what was believed - machine learning enables development of new model ...

AI projected to replace thousands of banking jobs ...

The Cloud

UTSA Open Cloud Institute supports Cloud research & launches certificate programme ...