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Primeur weekly 2016-03-29

Crowd computing

Tuberculosis to be tackled using crowd computing power ...

Quantum computing

Unlocking the gates to quantum computing ...

Focus on Europe

ISC to announce the 2016 Hans Meuer Award winning research paper ...

PRACE Ada Lovelace Award for HPC nominations in now open ...

Middleware

Bright Computing names Dan Kuczkowski as Senior Vice President of Worldwide Sales ...

Hardware

Intersect360 Research to present 8th HPC Budget Allocation Map: Budget Expectations ...

SC16 Student Cluster Competition still open till April 15, 2016 ...

Mellanox announces first 200Gb/s silicon photonics devices, doubling the performance in the QSFP form factor ...

Mellanox and InnoLight announce the availability and interoperability of 100Gb/s PSM4 transceivers at 1310 and 1550nm wavelengths ...

Lawrence Livermore National Laboratory and IBM collaborate to build brain-inspired supercomputer ...

Applications

KAUST IT Research Computing implements HPC Add-ons for research applications in order to automate the access to HPC resources ...

Could material defects actually improve solar cells? ...

NERSC announces 4th annual HPC Achievement Award winners ...

Research powers ahead with new supercomputer at University of Adelaide ...

Predicting severe hail storms ...

Honda selects IBM Watson IoT technology enabling real-time racing decisions for Formula One power unit operation ...

New computational method reveals significant degeneration of knee cartilage in overweight people ...

Breakthrough technology to improve cyber security ...

Researchers to develop new computing technology to minimize risks of data breaches ...

Record-speed data transmission could make Big Data more accessible ...

Robust network of connections between neurons performing similar tasks shows fundamentals of how brain circuits are wired ...

The Cloud

IBM opens Bluemix Garage in Europe to fuel Cloud development ...

GEANT and Amazon Web Services - breaking down barriers to cloud services adoption ...

Oracle unveils suite of breakthrough services to help simplify Cloud adoption by global corporations ...

New computational method reveals significant degeneration of knee cartilage in overweight people

24 Mar 2016 Joensuu - Osteoarthritis is a degenerative disease in which the articular cartilage protecting the joint starts to degenerate and wear off over time. The main risk factors of osteoarthritis are advanced age and overweight-induced significant stresses on the knee joint. Current imaging methods such as MRI and X-ray provide information about the thickness and composition of the cartilage, but they do not provide a quantitative estimate of the patient-specific risk of osteoarthritis or its progression.

Published inNature, a recent study from the University of Eastern Finland developed and validated a novel computational modelling method for the assessment of the patient-specific progression of osteoarthritis in the knee joint by using MRI data. The research group comprises researchers from the University of Eastern Finland and Lund University.

"The method we have developed is based on stresses experienced by the knee joint during walking, and these were simulated on a computer. Our idea was that walking-induced cumulative stresses that exceed a certain threshold will cause local degeneration in the articular cartilage of the knee", stated Postdoctoral Researcher Mika Mononen from the University of Eastern Finland's Department of Applied Physics.

The patient-specific estimates of the progression of osteoarthritis obtained by computer modelling were validated against four-year follow-up data from X-ray measurements, in which the thickness of the articular cartilage in the knee was evaluated by using the Kellgren-Lawrence method. For the validation of the model, two patient groups were established: the normal weight group and the overweight group.

In the normal weight group, the thickness of healthy cartilage did not change over the four-year follow-up, whereas significant degeneration was observed in the overweight group.

"The study shows that this new method, which is based on computer modelling, was able to predict similar changes in the articular cartilage of the knee as experimental follow-up data", Mika Mononen stated.

In the future, the method can serve as a new tool for making patient-specific prognoses on the progression of osteoarthritis. Furthermore, the method can be used for assessing the patient-specific effects of overweight on the future health of the knee joint as well as the success of clinical treatment such as menisectomy, a widely used surgical procedure.

Mononen M.E., Tanska P., Isaksson H. and Korhonen R.K. are the authors of the paper titled "A Novel Method to Simulate the Progression of Collagen Degeneration of Cartilage in the Knee: Data from the Osteoarthritis Initiative" .
Source: University of Eastern Finland

Back to Table of contents

Primeur weekly 2016-03-29

Crowd computing

Tuberculosis to be tackled using crowd computing power ...

Quantum computing

Unlocking the gates to quantum computing ...

Focus on Europe

ISC to announce the 2016 Hans Meuer Award winning research paper ...

PRACE Ada Lovelace Award for HPC nominations in now open ...

Middleware

Bright Computing names Dan Kuczkowski as Senior Vice President of Worldwide Sales ...

Hardware

Intersect360 Research to present 8th HPC Budget Allocation Map: Budget Expectations ...

SC16 Student Cluster Competition still open till April 15, 2016 ...

Mellanox announces first 200Gb/s silicon photonics devices, doubling the performance in the QSFP form factor ...

Mellanox and InnoLight announce the availability and interoperability of 100Gb/s PSM4 transceivers at 1310 and 1550nm wavelengths ...

Lawrence Livermore National Laboratory and IBM collaborate to build brain-inspired supercomputer ...

Applications

KAUST IT Research Computing implements HPC Add-ons for research applications in order to automate the access to HPC resources ...

Could material defects actually improve solar cells? ...

NERSC announces 4th annual HPC Achievement Award winners ...

Research powers ahead with new supercomputer at University of Adelaide ...

Predicting severe hail storms ...

Honda selects IBM Watson IoT technology enabling real-time racing decisions for Formula One power unit operation ...

New computational method reveals significant degeneration of knee cartilage in overweight people ...

Breakthrough technology to improve cyber security ...

Researchers to develop new computing technology to minimize risks of data breaches ...

Record-speed data transmission could make Big Data more accessible ...

Robust network of connections between neurons performing similar tasks shows fundamentals of how brain circuits are wired ...

The Cloud

IBM opens Bluemix Garage in Europe to fuel Cloud development ...

GEANT and Amazon Web Services - breaking down barriers to cloud services adoption ...

Oracle unveils suite of breakthrough services to help simplify Cloud adoption by global corporations ...