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Primeur weekly 2020-02-10

Exascale supercomputing

Tachyum's reference design will be used in a 2021 AI/HPC supercomputer ...

Quantum computing

Forschungszentrum Jülich to establish technology laboratory for quantum computers ...

FEFU scientists developed method to build up functional elements of quantum computers ...

New quantum switch turns metals into insulators ...

Focus on Europe

International Advanced Research Workshop on High Performance Computing to issue Call for Participation ...

EPSRC appoints Mark Parsons Director of Research Computing ...

e-IRG Workshop "Grand challenges of e-Infrastructures within the new ERA" to issue Call for Participation ...

BigDFT4CHEM wins the EXDCI Call for Spin-off Initiatives (SPI) ...

Eni unveils its new supercomputing system HPC5, the world's most powerful for industrial use ...

Tachyum CEO Dr. Radoslav Danilak discusses 'Bringing Slovakia to the Forefront of the Digital Age' at CEO Forum ...

Middleware

KU Leuven joins the iRODS Consortium ...

Sylabs has released SingularityPRO 3.5 ...

Hardware

DDN named finalist in Storage Magazine and SearchStorage 2019 Products of the Year awards ...

Fujitsu receives supercomputer order from Nagoya University's Information Technology Center ...

Controlling light with light ...

WekaIO recognized as a coolest Cloud company by CRN ...

Samsung to Advance High Performance Computing Systems with Launch of Industry's First 3rd-generation (16GB) HBM2E ...

Xperi enters into new patent and technology license agreement with SK hynix ...

Supermicro announces second quarter fiscal 2020 financial results ...

Applications

BSC European supercomputing centre that most has contributed to Pan-Cancer ...

March 2020 HPC User Forum will showcase AI, energy research and other HPC areas ...

Deep learning accurately forecasts heat waves and cold spells ...

Retina-inspired carbon nitride-based photonic synapses for selective detection of UV light ...

Computer simulation for understanding brain cancer growth ...

Gordon examining secure computation ...

Fusion squeeze, global image mapping, computing mental health, and Na+ batteries at Oak Ridge National Laboratory ...

SDSC supercomputer models improve Oregon/Washington coastal forecasts ...

Protein Data Bank archive adds new coronavirus protease structure ...

Computer simulation for understanding brain cancer growth

6 Feb 2020 Newcastle - The growth of brain cancers can be better understood with the help of a new computer platform developed by international scientists coordinated by Newcastle University.

Publishing in the journalMethods, the team from Newcastle University, the University of Cyprus, UCL and CERN describe how they have developed the three-dimensional model which brings together the macroscopic scale of tissue with the microscopic scale of individual cells. This allows the platform to realistically model cancer mechano-biology while maintaining the resolution power which makes it cost-effective.

Dr. Roman Bauer from the School of Computing, stated: "Built on top of the latest computing technologies, the BioDynaMo platform enables users to perform simulations on an increased scale and complexity making it possible to tackle challenging scientific research questions."

Although many specialised software tools exist, establishing this high-performance, general-purpose platform is a major step forward.

Jean de Montigny, PhD student from the Faculty of Medical Sciences, stated: "The advantage for scientists and medics is that BioDynaMo can be used on standard laptops or desktop computers and provides a software platform which can be used to easily create, run and visualise 3D agent-based biological simulations."

Glioma is a broad category of brain and spinal cord tumours that originate from neural stem cells and glial cells that support neurons. Treatment for patients - who tend to be older adults - involves surgery to remove as much of the tumour as possible followed by chemotherapy and radiotherapy.

By modelling the growth of a glioma, clinicians can better understand how a tumour may develop and progress. Cancer researchers could use however such models in the future to improve the outcome of pertinent therapeutic procedures.

This paper develops a three-dimensional in silico hybrid model of cancer, which describes the multi-variate phenotypic behaviour of tumour and host cells. The model encompasses the role of cell migration and adhesion, the influence of the extracellular matrix, the effects of oxygen and nutrient availability, and the signalling triggered by chemical cues and growth factors.

Involving CERN, which contributed its deep knowledge in large-scale computing to this collaboration with Newcastle University, the project has been supported by Intel.

Moreover, the University of Cyprus and UCL investigators contributed with their expertise in multiscale modelling.

Biodynamo is an international collaboration partially funded by the CERN Budget for Knowledge Transfer to Medical Applications, through a grant awarded in 2016.

The paper titled " An in silico hybrid continuum-/agent-based procedure to modelling cancer development: interrogating the interplay amongst glioma invasion, vascularity and necrosis " is authored by Jean de Montigny, Alexandros Iosif, Lukas Breitwieser, Marco Manca, Roman Bauer, and Vasileios Vavourakis.

The unique platform which can be used to help develop better treatments for glioma is freely available at https://biodynamo.org/ .

Source: Newcastle University

Back to Table of contents

Primeur weekly 2020-02-10

Exascale supercomputing

Tachyum's reference design will be used in a 2021 AI/HPC supercomputer ...

Quantum computing

Forschungszentrum Jülich to establish technology laboratory for quantum computers ...

FEFU scientists developed method to build up functional elements of quantum computers ...

New quantum switch turns metals into insulators ...

Focus on Europe

International Advanced Research Workshop on High Performance Computing to issue Call for Participation ...

EPSRC appoints Mark Parsons Director of Research Computing ...

e-IRG Workshop "Grand challenges of e-Infrastructures within the new ERA" to issue Call for Participation ...

BigDFT4CHEM wins the EXDCI Call for Spin-off Initiatives (SPI) ...

Eni unveils its new supercomputing system HPC5, the world's most powerful for industrial use ...

Tachyum CEO Dr. Radoslav Danilak discusses 'Bringing Slovakia to the Forefront of the Digital Age' at CEO Forum ...

Middleware

KU Leuven joins the iRODS Consortium ...

Sylabs has released SingularityPRO 3.5 ...

Hardware

DDN named finalist in Storage Magazine and SearchStorage 2019 Products of the Year awards ...

Fujitsu receives supercomputer order from Nagoya University's Information Technology Center ...

Controlling light with light ...

WekaIO recognized as a coolest Cloud company by CRN ...

Samsung to Advance High Performance Computing Systems with Launch of Industry's First 3rd-generation (16GB) HBM2E ...

Xperi enters into new patent and technology license agreement with SK hynix ...

Supermicro announces second quarter fiscal 2020 financial results ...

Applications

BSC European supercomputing centre that most has contributed to Pan-Cancer ...

March 2020 HPC User Forum will showcase AI, energy research and other HPC areas ...

Deep learning accurately forecasts heat waves and cold spells ...

Retina-inspired carbon nitride-based photonic synapses for selective detection of UV light ...

Computer simulation for understanding brain cancer growth ...

Gordon examining secure computation ...

Fusion squeeze, global image mapping, computing mental health, and Na+ batteries at Oak Ridge National Laboratory ...

SDSC supercomputer models improve Oregon/Washington coastal forecasts ...

Protein Data Bank archive adds new coronavirus protease structure ...