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Primeur weekly 2014-12-22

Focus

SimScale engineering simulation platform is perfectly running in a web browser now ...

EuroFlash

RSC Group has entered in the Top10 of the world leading supercomputer vendors by TOP500 list ...

ISC High Performance introduces workshops in 2015 ...

ADVA Optical Networking transforms fiber access networks with new Access Link Monitoring solution ...

Telindus Telecom deploys ADVA Optical Networking's encryption technology to secure operator network and Cloud services ...

Institute of Aircraft Design at the University of Stuttgart selects Bright Cluster Manager for its HPC data centre ...

Imec partners with Huawei on high-bandwidth optical data link technology ...

Six new projects enabling scientific discovery to start in 2015 ...

ENTRA: Better software cuts computer energy use ...

USFlash

Cray awarded $30 million contract from the Department of Defense High Performance Computing Modernization Programme ...

High Performance Computing Modernization Programme (HPCMP) doubles capabilities ...

Ancient wisdom boosts sustainability of biotech cotton ...

Compute Canada attracts High Performance Computing talent to lead upgrades to the national advanced research platform ...

Pacific Northwest National Laboratory a major contributor to Washington state economy ...

U.S. Department of Veterans Affairs taps IBM Watson to help accelerate and enhance care delivery ...

More than 100 teams expected for ASC15, road-showed at Melbourne and Nanjing ...

Stanford team combines logic, memory to build a 'high-rise' chip ...

Tulane has one of the world's fastest computers ...

Funding ended for University of California High-Performance AstroComputing Center ...

Simulations at NERSC help illuminate attosecond laser experiment findings ...

Riding a 100G InfiniBand backbone, InfiniCortex, the Intercontinental Supercomputing Architecture, debuts in New Orleans ...

Quantum physics just got less complicated ...

Switching to spintronics ...

Lasers, multiple languages support and more with wysiwyg R34 ...

Six new projects enabling scientific discovery to start in 2015


17 Dec 2014 Amsterdam - The Netherlands eScience Center has initiated six new projects in the areas of Environment and Sustainability, Life Sciences & eHealth, Humanities and Social Sciences and Physics and Beyond. The projects, scheduled to start in 2015, are collaborations with research teams from multiple Dutch academic groups and represent the latest step in the continued development of NLeSC's project portfolio.

The six projects result from two recent calls. Two projects will be funded in the areas of Humanities and Social Sciences. Project leaders Dr. Loro Aroyo and Prof. Piek Vossen will each receive funding to the value of 125K euro. Four more projects will receive funding to the value of 500K euro to address challenges in climate research, eChemistry and green genetics. NLeSC funds projects by the direct provision of cash and the in kind provision of eScience Research Engineers.

The six selected projects include the following:

  • DIVE+: Interacting with Historical Events in Linked Cultural Heritage, Dr. L. Aroyo, VU University Amsterdam

This project provides a basis for interpretation support in searching and browsing of heritage objects, where semantic information from existing collections plus open linked data vocabularies are linking collection objects to the events, people, locations and concepts that are depicted or associated with those objects. An innovative interface paradigm allows for browsing this network of data in an intuitive fashion supporting both digital humanities scholars and general audiences in their online explorations.

  • Visualizing uncertainty and perspectives, Prof. dr. P. Vossen, VU University Amsterdam

This project aims to develop a tool that visualizes subjectivity, perspective and uncertainty to make them controllable variables in Humanities research. The tool should allow users to compare information from different sources representing alternative perspectives and visualize subjectivity and uncertainty. Such a visualization enables improved and comprehensive source criticism, provides new directions of research and strengthens the methodology of digital humanities.

  • Environmental Re-Analysis of Urban areas: Quantifying high-resolution energy and water budgets of European cities (ERA-URBAN), Prof. dr. A.A.M. Holtslag, Wageningen University

Ongoing world-wide climate change and urbanization illustrate the need to understand urban hydrometeorology and its consequences for human thermal comfort and water management.

Limited availability of long-term geographical and hydrometeorological observations and limited computational capacity for urban scale simulations have so far hampered answering related scientific research questions. This project will develop an urban hydrometeorological archive that combines all available, rich and heterogeneous observations with multi-scale atmospheric and hydrological model results. The challenge is to make the data in the archive meaningful, insightful and useful for scientists, local-scale urban planners, policy makers, (local) companies and individual citizens.

  • 3D-e-Chem: Integrated eScience workflow to translate biological and chemical data into structure-based protein-ligand polypharmacology prediction, Dr. C. de Graaf, VU University Amsterdam

Many new protein targets have been discovered recently and it has been shown that clinical efficacy is often the result of polypharmacologicalaction of drug molecules, i.e. the interaction with more than one protein target. Efficient exploitation of chemical and biological information is hampered however, because a good approach to efficiently integrate large volumes of heterogeneous data from different disciplines is still missing. The data needs to be properly integrated in order to extract useful information that is manageable and applicable in various life science disciplines. This project will develop technologies to improve the integration of ligand and protein data for structure-based prediction of protein-ligand selectivity and polypharmacology.

  • Computational chemistry made easy, Prof. dr. L. Visscher, VU University Amsterdam

This project concerns the construction and efficient execution of computational chemistry work flows. This allows computational chemists to use the emerging massively parallel computing environments in an easy manner and focus on interpretation of scientific data rather than on tedious job submission procedures and manual data processing. This makes entirely new approaches possible in which a single researcher can model and analyze thousands of compounds with high-level quantum chemistry methods. This yields a wealth of detailed data (molecular structures, transition states, charge distributions, electronic excitation energies) to rationally design solar cells, reduce solvent losses in organic synthesis, tune catalysts, or develop better LEDs, to name just a few applications. The project goal will be realized by bringing concepts from distributed computing (efficient parallelization in heterogeneous environments) and bioinformatics (data management and workflow construction) to the field of computational chemistry.

  • Prediction of Candidate Genes for Traits Using Interoperable Genome Annotations and Literature, Prof. dr. R.G.F. Visser, Wageningen University
Plant breeding companies are facing a paradigm shift. From traditional quantitative trait loci (QTL) studies, breeders got an insight which region(s) to introgress in their elite germplasm, with the aim to improve traits of interest. However, genome annotations are becoming available for more and more (crop) species and researchers observe that a QTL region could easily include 1000 genes, positively or negatively affecting the desired phenotype. This project addresses the scientific challenge to utilize genome annotations and semantic interoperability with other databases, such as literature, for computer-assisted prioritization to determine which gene(s) is a candidate explaining the QTL. The application of the project results will be utilized in a better choice of parents for crossing in plant breeding, and as a perspective in the longer term, to enable precision breeding (genomics-assisted in silico design of an optimal genotype with a set of defined traits (e.g. quality and/or resistance), for production in a given environment and the subsequent strategy to breed for such a genotype), but are applicable in (animal, human and plant) genetics research in general.
Source: Netherlands eScience Center

Back to Table of contents

Primeur weekly 2014-12-22

Focus

SimScale engineering simulation platform is perfectly running in a web browser now ...

EuroFlash

RSC Group has entered in the Top10 of the world leading supercomputer vendors by TOP500 list ...

ISC High Performance introduces workshops in 2015 ...

ADVA Optical Networking transforms fiber access networks with new Access Link Monitoring solution ...

Telindus Telecom deploys ADVA Optical Networking's encryption technology to secure operator network and Cloud services ...

Institute of Aircraft Design at the University of Stuttgart selects Bright Cluster Manager for its HPC data centre ...

Imec partners with Huawei on high-bandwidth optical data link technology ...

Six new projects enabling scientific discovery to start in 2015 ...

ENTRA: Better software cuts computer energy use ...

USFlash

Cray awarded $30 million contract from the Department of Defense High Performance Computing Modernization Programme ...

High Performance Computing Modernization Programme (HPCMP) doubles capabilities ...

Ancient wisdom boosts sustainability of biotech cotton ...

Compute Canada attracts High Performance Computing talent to lead upgrades to the national advanced research platform ...

Pacific Northwest National Laboratory a major contributor to Washington state economy ...

U.S. Department of Veterans Affairs taps IBM Watson to help accelerate and enhance care delivery ...

More than 100 teams expected for ASC15, road-showed at Melbourne and Nanjing ...

Stanford team combines logic, memory to build a 'high-rise' chip ...

Tulane has one of the world's fastest computers ...

Funding ended for University of California High-Performance AstroComputing Center ...

Simulations at NERSC help illuminate attosecond laser experiment findings ...

Riding a 100G InfiniBand backbone, InfiniCortex, the Intercontinental Supercomputing Architecture, debuts in New Orleans ...

Quantum physics just got less complicated ...

Switching to spintronics ...

Lasers, multiple languages support and more with wysiwyg R34 ...