UT Austin researchers find hotspots of genetic instability in cancer using Stampede and Lonestar

The Vasquez Lab members, including: Karen Vasquez (front), James T. Delucio Regents Professor, Division of Pharmacology and Toxicology, University of Texas at Austin; and Albino Bacolla, Research Associate, University of Texas at Austin.
18 Jun 2015 Austin - Supercomputers have helped scientists find a surprising link between cross-shaped (or cruciform) pieces of DNA and human cancer, according to a study at The University of Texas at Austin (UT Austin). The UT Austin study found that small DNA cruciforms are mutagenic, altering DNA in a way that can increase risk of cancer in yeast, monkeys, and in humans. Lead researcher was Karen Vazquez said. Vasquez who is the James T. Delucio Regents Professor in the Division of Pharmacology and Toxicology at The University of Texas at Austin.
Vasquez sees a bright future in the intertwining of computation and the life sciences. "I think the potential of the computational analysis is mind-blowing. Bioinformatics and computational centers like TACC are critical for the next steps in science. It's an exciting time," she said.
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